No, the opposite. Be a tiny bit sympathetic. She is in a tough spot.
VCs have very, very specific boxes they like to invest in. At just the right stage. Just this sort of team. This sort of risk — but not that sort of risk. VC is about taking measured risk. Everyone measures that risk differently.
Nothing can be more uncomfortable then having a friend and/or someone you’ve known a long time not understand why you can’t invest, because it doesn’t fit your personal, specific box.
And …
If this VC friend believes in you, it’s just not the right fit for her … don’t alienate her. She can still support you with other investors in other ways, either now. Or later.